Core Support may be beneficial to:
- Enhance liver detoxification
- Support detoxification of toxins
- Support healthy estrogen metabolism
- Increase antioxidant protection and glutathione production
- Promote gastrointestinal health
The human body is exposed to a wide variety of toxins on a daily basis including chemicals found in foods, environmental toxins, and pharmaceuticals. The liver is the body’s main detoxification organ which provides enzyme systems that safely process and remove xenobiotics (foreign chemical substances) out of the body, as well as unhealthy hormone metabolites. These detoxification systems are very complex and require a variety of nutrients for optimal function. There are two main pathways of detoxification in the liver, known as phase I and phase II. In phase I, composed mainly of cytochrome P450 enzymes, non-reactive compounds undergo specific reactions which use oxygen to form a reactive site on the compound. Most pharmaceuticals are metabolized through Phase I biotransformation. This prepares the metabolite for the next step of detoxification. Phase II is a crucial step- if molecules from Phase I are not fully metabolized by Phase II conjugation they may cause free radical damage to proteins, RNA, and DNA within the cell. Phase II reactions result in the biotransformation of fat-soluble compounds into water-soluble compounds that can then be excreted in the urine, bile, or stool.