SIBO is a condition that occurs when there is an overabundance of commensal bacteria from the colon present in the small intestine. The health of the small intestines relies on balanced microbiota, and probiotics and immunoglobulins can contribute to that balance by having a positive influence on the intestinal environment, including pH, organism diversity, and immune signaling. Probiotics have been extensively studied and are characterized as having broad GI and immune benefits. Probiotics are live organisms and must be shelf stable through the expiration date, so they can be precisely delivered to the intestinal tract to have maximum benefit. Bacillus spores remain dormant in harsh environments until they reach more favorable environments like the human gastrointestinal tract. The combination of specific strains, particularly Bacillus coagulans, Bacillus clausii, and Bacillus subtilis, relieve symptoms for common GI complaints and reinforce healthy gut function. In the search for innovative ways to improve microbiome diversity, we have combined our blend of spore-forming probiotics alongside immunoglobulins uniquely shown to bind to bacteria and toxins, driving immune response.